ncRNA name | rno-miR-20b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat retinal endothelial cells (RECs) |
Methods | qRT-PCR, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | miR-20b is important for the regulation of VEGF-mediated changes in HRECs and rat retinal tissues under hyperglycemic conditions possibly via targeting AKT3. |
PubMed ID | 27421659 |
Year | 2016 |
Title | MiR-20b targets AKT3 and modulates vascular endothelial growth factor-mediated changes in diabetic retinopathy. |
Drug-related ncRNA | NO |
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